News
Phytonutrients in Apples & Strawberries Affect Blood Sugars
Polyphenols and phenolic acids from strawberry and apple may decrease glucose uptake by blocking transport through human intestinal cells, according to a new study.

The research suggests that some polyphenols, phenolic acids and tannins extracted from apples and strawberries may block the transport of glucose across intestinal tissues, potentially blunting post-meal glucose spikes.

"Our results indicate that unsweetened beverages rich in these dietary PPTs might provide a dietary mechanism to dampen, blunt or regulate intestinal sugar absorption, a potentially important factor in the management of diabetes and the metabolic syndrome," said Susana Manzano and Prof Gary Williamson, from the School of Food Science and Nutrition at the University of Leeds in the U.K.

They added that their study is the first to show an inhibition of glucose transport across intestinal tissue by phenolic fruit extracts, and further characterize the contribution of individual phenolic components for their role in the inhibition of glucose transport.

Source: NutraIngredients-USA.com 

Molecular Nutrition & Food Research
Volume 54, Issue 12, pages 1773–1780, doi: 10.1002/mnfr.201000019
"Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells"
Authors: S. Manzano, G. Williamson

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A Berry Good Test
(November 12, 2010)

New certified reference materials for measuring amounts of organic acids in dietary supplements formulated with berries -- cranberries, blueberries and bilberries - are now available to dietary supplement manufacturers to insure that the material is unadulterated. Organic acid ratios, which are specific to each type of berry, are a useful QC analytical tool for testing nutraceuticals that contain berry-derived ingredients..

Available through the National Institute of Standards and Technology (NIST), the seven reference materials were created as part of an ongoing collaboration to develop dietary supplement standards, involving NIST, the National Institutes of Health's Office of Dietary Supplements, and the FDA's Center for Drug Evaluation and Research.

Current analytical approaches for measuring organic acid ratios in berries, fruit juices, and dietary supplements have relied on the use of pure organic acid reference standards, which do not take into account the complexity of the whole berry.

For more information, see NIST's SRM website.

National Institute of Standards and Technology (NIST) (2010, November 11). New dietary supplement reference materials could be 'berry' useful. ScienceDaily. Retrieved November 12, 2010,

http://www.sciencedaily.com/releases/2010/11/101110113044.htm
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GMO's and Our Right to Know

(April 30, 2010)

For the first time ever, the U.S. Supreme Court is reviewing a case on genetically modified organisms (GMO) and their approval process. Monsanto Company is being sued because of concerns that their genetically engineered Roundup Ready alfalfa seeds can cross-contaminate nearby fields planted with organically produced alfalfa. It is also argued that because these GMO seeds have been engineered to resist a commonly used herbicide that Monsanto makes, killing off such unwanted plants would be extremely difficult.

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Natural Products Industry Resources

You are new to the natural products industry or a foreign company looking to enter the U.S. market and don't know where to start. We have compiled here some referrals and recommendations to get you on your way. Of course, the first contact that you should make is with us at Natural Discoveries, your one stop for consulting and product commercialization strategies. Our network of regulatory, technical, scientific, legal and other important contacts are available to insure a smooth and successful launch in the U.S. Reach out to us today to learn more about our services and track record of success.

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Recent Human Clinical Study on EstroG-100 Shows Positive Results with Menopausal Symptoms

(February 26, 2010)

A 2nd human clinical study on EstroG-100™, a patented proprietary botanical blend found in SunBio’s EstroBalance used for the management of menopausal symptoms, was recently completed. The original, first human clinical study took place over 12 months and results showed significant benefits 5X greater than placebo with the primary menopausal end points (Night Sweats, Hot Flashes, Vaginal Dryness, and Discomfort/ Mood.).

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Industry Responds to Proposed McCain Bill

from Nutrition Business Journal Online   (February 9, 2010)


In the wake of the U.S. Anti-Doping Agency’s (USADA) “Supplement Safety Now” campaign, Senator John McCain last week introduced the Dietary Supplement Safety Act of 2010, which is aimed at improving the current level of safety and transparency in the U.S. supplement industry. If signed into law, the legislation would alter portions of the Dietary Supplement Health and Education Act (DSHEA) of 1994. Among the major changes would be a requirement for all supplement manufacturers to go through an annual registration process that would include disclosure of all ingredients contained in products. Additionally, the new law would do away with the current grandfather clause for dietary supplement ingredients that were on the market prior to DSHEA’s passage in 1994. This means that all ingredients would be subject to a new list of accepted dietary ingredients determined by the Secretary of Health and Human Services (HHS) office. Further, instead of only reporting serious adverse events, manufacturers would be required to report even minor adverse events related to their products. Retailers would also be affected by the bill, as they would be required to ensure that all supplement manufacturers’ documentation is compliant with the U.S. Food and Drug Administration (FDA).

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Magnesium May Boost Brain Power

 

February 3, 2010

Neuroscientists at MIT and Tsinghua University in Beijing show that increasing brain magnesium with a new compound enhanced learning abilities, working memory, and short- and long-term memory in rats. The dietary supplement also boosted older rats’ ability to perform a variety of learning tests.

Magnesium, an essential element, is found in dark, leafy vegetables such as spinach and in some fruits. Those who get less than 400 milligrams daily are at risk for allergies, asthma and heart disease, among other conditions. In 2004, Guosong Liu and colleagues at MIT discovered that magnesium might have a positive influence onlearning and memory. They followed up by developing a new magnesium compound — magnesium-L-threonate (MgT) — that is more effective than conventional oral supplements at boosting magnesium in the brain, and tested it on rats

“We found that elevation of brain magnesium led to significant enhancement of spatial and associative memory in both young and aged rats,” said Liu, now director of the Center forLearning and Memory at Tsinghua University. “If MgT is shown to be safe and effective in humans, these results may have a significant impact on public health.” Further studies will focus on the safety and efficacy of Mg T in humans.

“Enhancement of Learning and Memory by Elevating Brain Magnesium,” Inna Slutsky, Nashat Abumaria, Long-Jun Wu, Chao Huang, Ling Zhang, Bo Li, Xiang Zhao, Arvind Govindarajan, Ming-Gao Zhao, Min Zhuo, Susumu Tonegawa and Guosong Liu in Neuron, Jan. 28, 2010.

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Nano curcumin could boost spice’s health benefits

Stephen Daniells -  November 18, 2009


Nano-sized curcumin capsules may boost the body’s uptake of the ingredient, and enhance its potential to prevent colon cancer and Alzheimer’s disease, suggests a new study from Japan.

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New Research in Exercise & Immunity

David Mastroianni - November 11, 2009

Does regular exercise enhance immune function? Should you work out when you have a cold or the flu? Everyone who is active, whether a world class athlete or weekend warrior, seems to have their own strategy when it comes to training during illness. But what does the latest research say when it comes to exercising and its effect on immune function?

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Coffee may decrease the risk of Alzheimer’s
Tuesday, 10 November 2009 00:00
Peter Leighton - November 10, 2009

Drinking between three and five cups of coffee a day in middle age could decrease the risk of dementia and Alzheimer's disease by 65 per cent, says a new study from Scandinavia.

Data from participants of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study showed that, while tea drinking was not associated with dementia risk, drinking coffee in middle age may significantly reduced the risk of dementia later in life.
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